anti-CST3 / Cystatin C antibody

anti-CST3 / Cystatin C antibody for ELISA and Human

Cell Biology and Cellular Response antibody; Cell Death antibody; Controls and Markers antibody; Developmental Biology antibody


Product Description Mouse Monoclonal antibody recognizes CST3 / Cystatin C
Tested Reactivity Hu
Tested Application ELISA
Host Mouse
Clonality Monoclonal
Isotype IgG1
Target Name CST3 / Cystatin C
Antigen Species Human
Immunogen Recombinant human cystatin c protein.
Conjugation Un-conjugated
Alternate Names Cystatin-C; Neuroendocrine basic polypeptide; Post-gamma-globulin; ARMD11; Cystatin-3; Gamma-trace

Application Instructions

Application Suggestion
Tested Application Dilution
ELISA0.5 µg/ml
Application Note Sandwich ELISA (Capture antibody - Detection antibody):
ARG54134 (4 µg/ml) - ARG54135 (0.5 µg/ml)

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Observed Size 13 kDa


Form Liquid
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 1471 Human CST3

Swiss-port # P01034 Human Cystatin-C

Gene Symbol CST3
Gene Full Name cystatin C
Background Cystatin C or cystatin 3 (formerly gamma trace, post-gamma-globulin or neuroendocrine basic polypeptide), a protein encoded by the CST3 gene,is mainly used as a biomarker of kidney function. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid (a specific type of protein deposition), such as Alzheimer´s disease. In humans, all cells with a nucleus (cell core containing the DNA) produce cystatin C as a chain of 120 amino acids. It is found in virtually all tissues and body fluids. It is a potent inhibitor of lysosomal proteinases (enzymes from a special subunit of the cell that break down proteins) and probably one of the most important extracellular inhibitors of cysteine proteases (it prevents the breakdown of proteins outside the cell by a specific type of protein degrading enzymes). Cystatin C belongs to the type 2 cystatin gene family.
Function As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity. [UniProt]
Research Area Cell Biology and Cellular Response antibody; Cell Death antibody; Controls and Markers antibody; Developmental Biology antibody
Calculated MW 16 kDa
PTM The Thr-25 variant is O-glycosylated with a core 1 or possibly core 8 glycan. The signal peptide of the O-glycosylated Thr-25 variant is cleaved between Ala-20 and Val-21.

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  • ARG54135 anti-CST3 / Cystatin C antibody ELISA image

    Standard Curve: Capture antibody: ARG54134 anti-CST3 / Cystatin C antibody at 4 µg/ml; Detector antibody: ARG54135 anti-CST3 / Cystatin C antibody at 0.5 µg/ml. These products result of a typical standard run with optical density reading at 450 nm.