ARG46992
anti-CTDSPL2 antibody
anti-CTDSPL2 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes CTDSPL2 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Target Name | CTDSPL2 |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human CTDSPL2. |
| Conjugation | Un-conjugated |
| Alternate Names | CTDSPL2; CTD small phosphatase-like protein 2; SCP4; Small C-terminal domain phosphatase 4; Small CTD phosphatase 4 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A |
| Buffer | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q05D32 Human CTD small phosphatase-like protein 2 |
|---|---|
| Gene Symbol | CTDSPL2 |
| Gene Full Name | CTD small phosphatase-like protein 2 |
| Background | Enables RNA polymerase II CTD heptapeptide repeat phosphatase activity. Involved in positive regulation of gluconeogenesis. Located in nucleus. [provided by Alliance of Genome Resources, Jun 2026] |
| Function | Serine/threonine phosphatase that promotes gluconeogenesis by dephosphorylating FOXO1 and FOXO3A, promoting their nuclear retention and enhancing their transcriptional activity on PCK1 and G6PC1, key enzymes in hepatic gluconeogenesis. [UniProt] |
| Cellular Localization | Nucleus. [UniProt] |
| Calculated MW | 53 kDa |
| PTM | Acetylation; Phosphoprotein. [UniProt] |
