ARG45706
anti-Cadherin 15 antibody
anti-Cadherin 15 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Cadherin 15 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Cadherin 15 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human Cadherin 15. |
| Conjugation | Un-conjugated |
| Alternate Names | CDH15; cadherin 15, type 1, M-cadherin (myotubule); CDHM; CDH14; MRD3; MCAD; Cadherin-15; Cadherin-14; Muscle cadherin; M-cadherin; CDH3 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 130 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CDH15 |
| Gene Full Name | cadherin 15, type 1, M-cadherin (myotubule) |
| Background | This gene is a member of the cadherin superfamily of genes, encoding calcium-dependent intercellular adhesion glycoproteins. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. The protein is thought to be essential for the control of morphogenetic processes, specifically myogenesis, and may provide a trigger for terminal muscle cell differentiation. [provided by RefSeq, Jul 2008] |
| Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. M-cadherin is part of the myogenic program and may provide a trigger for terminal muscle differentiation. [UniProt] |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein. [UniProt] |
| Calculated MW | 89 kDa |
| PTM | Cleavage on pair of basic residues; Glycoprotein. [UniProt] |
Images (6) Click the Picture to Zoom In
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ARG45706 anti-Cadherin 15 antibody WB image
Western blot: Hela stained with ARG45706 anti-Cadherin 15 antibody at 0.5 μg/ml dilution.
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ARG45706 anti-Cadherin 15 antibody FACS image
Flow Cytometry: C2C12 stained with ARG45706 anti-Cadherin 15 antibody at 1 µg/10^6 cells dilution.
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ARG45706 anti-Cadherin 15 antibody IHC-P image
Immunohistochemistry: Rat skeletal muscle stained with ARG45706 anti-Cadherin 15 antibody at 2 μg/ml dilution.
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ARG45706 anti-Cadherin 15 antibody WB image
Western blot: L6 stained with ARG45706 anti-Cadherin 15 antibody at 0.5 μg/ml dilution.
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ARG45706 anti-Cadherin 15 antibody IHC-P image
Immunohistochemistry: Mouse skeletal muscle stained with ARG45706 anti-Cadherin 15 antibody at 2 μg/ml dilution.
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ARG45706 anti-Cadherin 15 antibody WB image
Western blot: C2C12 stained with ARG45706 anti-Cadherin 15 antibody at 0.5 μg/ml dilution.
