ARG10498
anti-Calcitonin antibody [24B2]
anti-Calcitonin antibody [24B2] for ELISA,Western blot and Human
Cancer antibody; Cell Biology and Cellular Response antibody; Neuroscience antibody; Signaling Transduction antibody
Overview
| Product Description | Mouse Monoclonal antibody [24B2] recognizes Calcitonin |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, WB |
| Specificity | This clone reacts Human calcitonin and procalcitonin |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 24B2 |
| Isotype | IgG1 |
| Target Name | Calcitonin |
| Antigen Species | Human |
| Immunogen | Balb/c mice immunized with calcitonin conjugated with carrier protein. |
| Conjugation | Un-conjugated |
| Full Name | calcitonin-related polypeptide alpha |
| Alternate Names | KC; CGRP-I; Calcitonin gene-related peptide 1; CGRP1; CALC1; Calcitonin gene-related peptide I; Alpha-type CGRP; CGRP; CT |
Application Instructions
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
|---|---|
| Calculated MW | 14 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A affinity purified. |
| Buffer | PBS (pH.2)) and 0.1 % Sodium azide |
| Preservative | 0.1 % Sodium azide |
| Concentration | 1.0-2.0 mg/ml |
| Storage instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database links | |
|---|---|
| Gene Symbol | CALCA |
| Gene Full Name | calcitonin-related polypeptide alpha |
| Background | This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2014] |
| Function | CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP. [UniProt] |
| Research Area | Cancer antibody; Cell Biology and Cellular Response antibody; Neuroscience antibody; Signaling Transduction antibody |
