ARG46924
anti-Calpain 15/SOLH antibody
anti-Calpain 15/SOLH antibody for Western blot and Human
Overview
| Product Description | Mouse Polyclonal antibody recognizes Calpain 15/SOLH |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Mouse |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Calpain 15/SOLH |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human Calpain 15/SOLH. |
| Conjugation | Un-conjugated |
| Alternate Names | CAPN15; Calpain-15; SOLH; Small optic lobes homolog |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CAPN15 |
| Gene Full Name | Calpain-15 |
| Background | This gene encodes a protein containing zinc-finger-like repeats and a calpain-like protease domain. The encoded protein may function as a transcription factor, RNA-binding protein, or in protein-protein interactions during visual system development. [provided by RefSeq, Jul 2008] |
| Function | Calcium-dependent cysteine protease that functions as a non-proteasomal, ubiquitin-directed protease regulating cell adhesion through cleavage of E-cadherin/CDH1. Binds to ubiquitinated proteins via its N-terminal, preferentially recognizing longer polyubiquitin chains including both 'Lys-48- and 'Lys-63'-linked chains. Recognizes the ubiquitinated E-cadherin-catenin complex and cleaves E-cadherin in a calcium- and ubiquitination-dependent manner resulting in lysosomal degradation of the resultant fragment. [UniProt] |
| Calculated MW | 117 kDa |
| PTM | Phosphoprotein. [UniProt] |
