ARG46921
anti-Carbonic Anhydrase 5B/CA5B antibody
anti-Carbonic Anhydrase 5B/CA5B antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,ELISA and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes Carbonic Anhydrase 5B/CA5B |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, IHC-P, IP |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Target Name | Carbonic Anhydrase 5B/CA5B |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human Carbonic Anhydrase 5B/CA5B. |
| Conjugation | Un-conjugated |
| Alternate Names | CA5B; Carbonic anhydrase 5B; mitochondrial; Carbonate dehydratase VB; Carbonic anhydrase VB; CA-VB |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A |
| Buffer | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9Y2D0 Human Carbonic anhydrase 5B, mitochondrial |
|---|---|
| Gene Symbol | CA5B |
| Gene Full Name | Carbonic anhydrase 5B, mitochondrial |
| Background | Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes carbonic anhydrase 5B. CA5B, and the related CA5A gene, has its expression localized in the mitochondria though CA5B has a wider tissue distribution than CA5A, which is restricted to the liver, kidneys, and skeletal muscle. A carbonic anhydrase pseudogene (CA5BP1) is adjacent to the CA5B gene and these two loci produce CA5BP1-CA5B readthrough transcripts. [provided by RefSeq, Jan 2019] |
| Function | Mitochondrial carbonic anhydrase that catalyzes the reversible conversion of carbon dioxide to bicarbonate/HCO3. [UniProt] |
| Calculated MW | 36 kDa |
