ARG45516
anti-Carma 3 antibody
anti-Carma 3 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Carma 3 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Carma 3 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human Carma 3. |
| Conjugation | Un-conjugated |
| Alternate Names | CARD10; Caspase Recruitment Domain Family Member 10; CARMA3; BIMP1; Caspase Recruitment Domain-Containing Protein 10; CARD-Containing MAGUK Protein 3; Carma 3; Caspase Recruitment Domain Family, Member 10; Bcl10 Binding Protein And Activator Of NFKB; CARD-Containing MAGUK 3 Protein; IMD89 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 116 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P58660 Mouse Caspase recruitment domain-containing protein 10 Swiss-port # Q9BWT7 Human Caspase recruitment domain-containing protein 10 |
|---|---|
| Gene Symbol | CARD10 |
| Gene Full Name | Caspase Recruitment Domain Family Member 10 |
| Background | The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB; see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).[supplied by OMIM, Mar 2008] |
| Function | Scaffold protein that plays an important role in mediating the activation of NF-kappa-B via BCL10 or EGFR. [UniProt] |
| Cellular Localization | Cytoplasm. [UniProt] |
| Calculated MW | 116 kDa |
| PTM | Phosphoprotein. [UniProt] |
Images (6) Click the Picture to Zoom In
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ARG45516 anti-Carma 3 antibody IHC-P image
Immunohistochemistry: Human bladder cancer stained with ARG45516 anti-Carma 3 antibody at 2 μg/ml dilution.
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ARG45516 anti-Carma 3 antibody WB image
Western blot: Human Hacat stained with ARG45516 anti-Carma 3 antibody at 0.5 μg/ml dilution.
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ARG45516 anti-Carma 3 antibody FACS image
Flow Cytometry: HepG2 stained with ARG45516 anti-Carma 3 antibody at 1 µg/10^6 cells dilution.
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ARG45516 anti-Carma 3 antibody IHC-P image
Immunohistochemistry: Rat kidney stained with ARG45516 anti-Carma 3 antibody at 2 μg/ml dilution.
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ARG45516 anti-Carma 3 antibody IHC-P image
Immunohistochemistry: Mouse kidney stained with ARG45516 anti-Carma 3 antibody at 2 μg/ml dilution.
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ARG45516 anti-Carma 3 antibody WB image
Western blot: Mouse kidney stained with ARG45516 anti-Carma 3 antibody at 0.5 μg/ml dilution.
