ARG67281
anti-Choline Acetyltransferase antibody
anti-Choline Acetyltransferase antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Monoclonal antibody recognizes Choline Acetyltransferase |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, IP, WB |
| Host | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG,Kappa |
| Target Name | Choline Acetyltransferase |
| Conjugation | Un-conjugated |
| Alternate Names | CHAT; Choline O-Acetyltransferase ; CHOACTase; Choline Acetylase; EC 2.3.1.6; Acetyl CoA:Choline O-Acetyltransferase; Choline Acetyltransferase; EC 2.3.1; CMS1A2; CMS1A; CMS6; ChAT |
Application Instructions
| Application Suggestion |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A |
| Buffer | PBS, 0.05% Proclin 300, 50% glycerol and 0.05% BSA |
| Preservative | 0.05% Proclin 300 |
| Stabilizer | 50% glycerol and 0.05% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CHAT |
| Gene Full Name | Choline O-Acetyltransferase |
| Background | This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010] |
| Function | Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses. [UniProt] |
| Calculated MW | 83 kDa |
Images (3) Click the Picture to Zoom In
-
ARG67281 anti-Choline Acetyltransferase antibody WB image
Western blot: SH-SY5Y stained with ARG67281 anti-Choline Acetyltransferase antibody.
-
ARG67281 anti-Choline Acetyltransferase antibody WB image
Western blot: Mouse brain stained with ARG67281 anti-Choline Acetyltransferase antibody.
-
ARG67281 anti-Choline Acetyltransferase antibody WB image
Western blot: Rat brain stained with ARG67281 anti-Choline Acetyltransferase antibody.
