ARG10083

anti-Colorectal carcinoma antibody [Y94]

anti-Colorectal carcinoma antibody [Y94] for IHC-Formalin-fixed paraffin-embedded sections and Human

Controls and Markers antibody

Overview

Product Description Mouse Monoclonal antibody [Y94] recognizes Colorectal Carcinoma
Tested Reactivity Hu
Tested Application IHC-P
Host Mouse
Clonality Monoclonal
Clone Y94
Isotype IgG1,k
Target Name Colorectal carcinoma
Antigen Species Human
Immunogen Human colorectal carcinoma
Conjugation Un-conjugated

Application Instructions

Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Protein G affinity purified
Buffer 0.01M PBS (pH 7.0)
Concentration 1 mg/ml
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Background Colorectal carcinoma is the cancer developed in the colon or rectum of the digestive system. In developed countries, it is the most common cancer in aging population. Genetic deposition and a less active life style contribute to the development of the cancer. Molecular pathological study showed that altered Wnt-APC-β-catenim signalling pathway, mutated p53, and deactivated TGF-β and DCC (Deleted in Colon Cancer) are involved with the pathogenesis. The cancer is currently screened with a fecal occult blood test in people over 50 years old and the malignancy is confirmed by tumour biopsy. The search for specific biomarker for non-invasive test is still ongoing. Tumour associated antigen, TAG-72, is a high molecular weight glycoprotein found at the cell surface in a variety of cancers including gastric cancer, ovarian cancer, colon cancer, breast cancer and pancreatic cancer. It has been used as a tumour marker and therapeutic target for cancer treatment.
Resrarch Area Controls and Markers antibody