ARG20536

anti-Cpn 10 antibody (PerCP)

anti-Cpn 10 antibody (PerCP) for Immunohistochemistry,ICC/IF,ELISA and Dog,Human,Mouse,Rat,Xenopus laevis,Bovine,Guinea pig,Pig,Rabbit,Sheep

Metabolism antibody; Signaling Transduction antibody

Overview

Product Description PerCP-conjugated Rabbit Polyclonal antibody recognizes Cpn 10
Tested Reactivity Hu, Ms, Rat, Bov, Dog, Gpig, Pig, Rb, Sheep, Xenopus laevis
Tested Application ELISA, ICC/IF, IHC
Host Rabbit
Clonality Polyclonal
Target Name Cpn 10
Antigen Species Human
Immunogen Synthetic peptide around aa. 91-101 of Human Cpn10.
Conjugation PerCP
Full Name heat shock 10kDa protein 1
Alternate Names HSP10; 10 kDa chaperonin; CPN10; Early-pregnancy factor; Hsp10; GROES; EPF; Chaperonin 10; 10 kDa heat shock protein, mitochondrial

Application Instructions

Application Suggestion
Tested Application Dilution
ELISAAssay-dependent
ICC/IFAssay-dependent
IHC1:100
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Calculated MW 11 kDa

Properties

Form Liquid
Purification Purification with Protein A.
Buffer PBS (pH 7.3) and 0.02% Sodium azide
Preservative 0.02% Sodium azide
Concentration 1 mg/ml
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Keep the antibody in the dark and keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 15528 Mouse HSPE1

GeneID: 281833 Bovine HSPE1

GeneID: 3336 Human HSPE1

Gene Symbol HSPE1
Gene Full Name heat shock 10kDa protein 1
Background Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (Hsp10s). Cpn10 acts as a co-chaperone and interacts with the Hsp60 family to promote proper folding of polypeptides. Cpn10 and Cpn60 both exhibit sevenfold axis of symmetry and function as a team in the protein folding and assembly process. Cpn10 has been located in human platelets, but is also present in human maternal serum. It has been reported that human Cpn10 is identical with early pregnancy factor, which is involved in control over cell growth and development. This identification suggest that Cpn10 may act like a hormone in stressful situations such as pregnancy.
Function Eukaryotic CPN10 homolog which is essential for mitochondrial protein biogenesis, together with CPN60. Binds to CPN60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. [UniProt]
Cellular Localization Mitochondrion Matrix
Research Area Metabolism antibody; Signaling Transduction antibody