ARG46121
anti-DELE1 antibody
anti-DELE1 antibody for Western blot and Human,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes DELE1 |
|---|---|
| Tested Reactivity | Hu, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | DELE1 |
| Antigen Species | Human |
| Immunogen | A 18 amino acid synthetic peptide within the first 50 amino acids of human DELE1. |
| Conjugation | Un-conjugated |
| Alternate Names | KIAA0141; KIAA0141; DELE; DELE; DELE; Death ligand signal enhancer |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -171°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | KIAA0141 |
| Gene Full Name | KIAA0141 |
| Background | Enables protein kinase binding activity and protein serine/threonine kinase activator activity. Involved in several processes, including HRI-mediated signaling; positive regulation of mitophagy; and response to iron ion starvation. Located in mitochondrial inner membrane. Is active in cytosol and mitochondrial outer membrane. [provided by Alliance of Genome Resources, Jul 2025] |
| Function | Protein kinase activator that acts as a key activator of the integrated stress response (ISR) following various stresses, such as iron deficiency, mitochondrial stress or mitochondrial DNA breaks. [UniProt] |
| Cellular Localization | Cytoplasm; Mitochondrion inner membrane; Cytosol. [UniProt] |
| Calculated MW | 56 kDa |
| PTM | Ubl conjugation. [UniProt] |
