ARG45745
anti-DHPS antibody
anti-DHPS antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes DHPS |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | DHPS |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human DHPS. |
| Conjugation | Un-conjugated |
| Alternate Names | DHPS; MIG13; EC 2.5.1.46; DHS; DS; Deoxyhypusine synthase |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Observed Size | 41 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | DHPS |
| Gene Full Name | deoxyhypusine synthase |
| Background | This gene encodes a protein that is required for the formation of hypusine, a unique amino acid formed by the posttranslational modification of only one protein, eukaryotic translation initiation factor 5A. The encoded protein catalyzes the first step in hypusine formation by transferring the butylamine moiety of spermidine to a specific lysine residue of the eukaryotic translation initiation factor 5A precursor, forming an intermediate deoxyhypusine residue. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2011] |
| Function | Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. [UniProt] |
| Cellular Localization | Cytoplasm; Cytosol. [UniProt] |
| Calculated MW | 41 kDa |
| PTM | Phosphoprotein. [UniProt] |
Images (5) Click the Picture to Zoom In
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ARG45745 anti-DHPS antibody IHC-P image
Immunohistochemistry: Human lung cancer stained with ARG45745 anti-DHPS antibody at 2 μg/ml dilution.
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ARG45745 anti-DHPS antibody ICC/IF image
Immunofluorescence: MCF-7 stained with ARG45745 anti-DHPS antibody at 5 μg/ml dilution.
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ARG45745 anti-DHPS antibody WB image
Western blot: Hela and MCF-7 stained with ARG45745 anti-DHPS antibody at 0.5 μg/ml dilution.
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ARG45745 anti-DHPS antibody FACS image
Flow Cytometry: K562 stained with ARG45745 anti-DHPS antibody at 1 µg/10^6 cells dilution.
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ARG45745 anti-DHPS antibody WB image
Western blot: Rat testis stained with ARG45745 anti-DHPS antibody at 0.5 μg/ml dilution.
