ARG52260

anti-DOPA Decarboxylase antibody

anti-DOPA Decarboxylase antibody for Western blot and Bovine,Dog,Guinea pig,Human,Rabbit,Rat,Sheep

Cancer antibody; Metabolism antibody; Neuroscience antibody

Overview

Product Description Rabbit Polyclonal antibody recognizes DOPA Decarboxylase
Tested Reactivity Hu, Rat, Bov, Dog, Gpig, Rb, Sheep
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name DOPA Decarboxylase
Antigen Species Human
Immunogen Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH
Conjugation Un-conjugated
Alternate Names DOPA decarboxylase; AADC; DDC; Aromatic-L-amino-acid decarboxylase; EC 4.1.1.28

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:1,000
Application Note Specific for the ~55k DDC protein
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity Purified
Buffer 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol
Stabilizer 0.1 mg/ml BSA, 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 100135516 Guinea pig DDC

GeneID: 1644 Human DDC

GeneID: 24311 Rat DDC

Gene Symbol DDC
Gene Full Name dopa decarboxylase (aromatic L-amino acid decarboxylase)
Background DOPA decarboxylase (aromatic L-amino acid decarboxylase, AADC; DDC) catalyzes the second reaction in the biosynthesis of catecholamines and serotonin (Waymire and Haycock, 2002; Berry et al., 1996; Haycock et al., 2003). It is also involved in the biosynthesis of trace amines. DDC antibodies can therefore be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999).
Research Area Cancer antibody; Metabolism antibody; Neuroscience antibody
Calculated MW 54 kDa

Images (1) Click the Picture to Zoom In

  • ARG52260 anti-DOPA Decarboxylase antibody WB image

    Western Blot: 20 ug of human caudate lysate showing specific immunolabeling of the ~55k DOPA Decarboxylase protein stained with DOPA Decarboxylase antibody (ARG52260).