anti-DR3 / TNFRSF25 antibody

anti-DR3 / TNFRSF25 antibody for ICC/IF,IHC-Frozen sections,Western blot and Human,Mouse,Rat

Cell Biology and Cellular Response antibody; Cell Death antibody; Signaling Transduction antibody


Product Description

Rabbit Polyclonal antibody recognizes DR3 / TNFRSF25

Tested Reactivity Hu, Ms, Rat
Tested Application ICC/IF, IHC-Fr, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name DR3 / TNFRSF25
Antigen Species Human
Immunogen Peptide corresponding to the extracellular domain of human DR3 precursor (accession no. AAQ88676).
Conjugation Un-conjugated
Alternate Names WSL-1; Apo-3; Apoptosis-mediating receptor TRAMP; DDR3; DR3; Protein WSL; Protein WSL-1; TRAMP; Apoptosis-inducing receptor AIR; TNFRSF12; Death receptor 3; LARD; Apoptosis-mediating receptor DR3; TR3; APO-3; Lymphocyte-associated receptor of death; Tumor necrosis factor receptor superfamily member 25; WSL-LR

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF10 µg/ml
WB1 µg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Purification Immunogen affinity purified
Buffer PBS (pH 7.4) and 0.02 % Sodium azide.
Preservative 0.02 % Sodium azide
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 85030 Mouse TNFRSF25

GeneID: 8718 Human TNFRSF25

Swiss-port # Q93038 Human Tumor necrosis factor receptor superfamily member 25

Gene Symbol TNFRSF25
Gene Full Name tumor necrosis factor receptor superfamily, member 25
Background Apoptosis is induced by certain cytokinesincluding TNF and Fas ligand of the TNF familythrough their death domain-containing receptors,TNFR1 and Fas. Another cell death receptorwas recently identified and designated DR3,Wsl-1, Apo-3, TRAMP, and LARD. DR3 iswidely expressed in tissues enriched inlymphocytes including peripheral blood, thymus,and spleen. Like TNFR1, DR3 inducesapoptosis and NF- B activation.
Function Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis. [UniProt]
Research Area Cell Biology and Cellular Response antibody; Cell Death antibody; Signaling Transduction antibody
Calculated MW 45 kDa
PTM Glycosylated.

Images (2) Click the Picture to Zoom In

  • ARG54394 anti-DR3 / TNFRSF25 antibody WB image

    Western blot: Jurkat cell lysate stained with ARG54394 anti-DR3 antibody at 1 µg/ml dilution.

  • ARG54394 anti-DR3 / TNFRSF25 antibody ICC/IF image

    Immunocytochemistry: Jurkat cells stained with ARG54394 anti-DR3 antibody at 10 µg/ml.