ARG40677

anti-Desmoglein 3 antibody

anti-Desmoglein 3 antibody for Western blot,Flow cytometry and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes Desmoglein 3
Tested Reactivity Hu
Predict Reactivity Ms, Rat
Tested Application FACS, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name Desmoglein 3
Antigen Species Human
Immunogen Synthetic peptide of Human Desmoglein 3.
Conjugation Un-conjugated
Full Name desmoglein 3
Alternate Names PVA; 130 kDa pemphigus vulgaris antigen; CDHF6; Cadherin family member 6; Desmoglein-3

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1:20
WB1:2000 - 1:10000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purified.
Buffer 50 nM Tris-Glycine (pH 7.4), 0.15M NaCl, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA.
Preservative 0.01% Sodium azide
Stabilizer 40% Glycerol and 0.05% BSA
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 1830 Human DSG3

Swiss-port # P32926 Human Desmoglein-3

Gene Symbol DSG3
Gene Full Name desmoglein 3
Background Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris. [provided by RefSeq, Jul 2008]
Function Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. [UniProt]
Cellular Localization Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome. [UniProt]
Calculated MW 108 kDa