anti-Dopamine beta Hydroxylase antibody

anti-Dopamine beta Hydroxylase antibody for Western blot and Human,Primates

Cancer antibody; Metabolism antibody; Neuroscience antibody


Product Description Sheep Polyclonal antibody recognizes Dopamine beta Hydroxylase
Tested Reactivity Hu, NHuPrm
Tested Application WB
Host Sheep
Clonality Polyclonal
Isotype IgG
Target Name Dopamine beta Hydroxylase
Antigen Species Human
Immunogen Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH
Conjugation Un-conjugated
Alternate Names EC; DBM; Dopamine beta-monooxygenase; Dopamine beta-hydroxylase

Application Instructions

Application Suggestion
Tested Application Dilution
Application Note Specific for the ~75k DBH protein in Western blots
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Purification Affinity Purified
Buffer 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol
Stabilizer 0.1 mg/ml BSA, 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 1621 Human DBH

Swiss-port # P09172 Human Dopamine beta-hydroxylase

Gene Symbol DBH
Gene Full Name dopamine beta-hydroxylase (dopamine beta-monooxygenase)
Background DBH catalyzes the conversion of dopamine to norepinephrine and serves as a marker of noradrenergic cells. DBH antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999). The expression of DBH is also elevated during stress (Sabban and Kvetnansky, 2001).
Research Area Cancer antibody; Metabolism antibody; Neuroscience antibody
Calculated MW 69 kDa
PTM N-glycosylated.
Proteolytic cleavage after the membrane-anchor leads to the release of the soluble form.

Images (1) Click the Picture to Zoom In

  • ARG52262 anti-Dopamine beta Hydroxylase antibody WB image

    Western Blot: 20 ug of human adrenal medulla lysate showing specific immunolabeling of the ~75k DBH protein stained with Dopamine-Hydroxylase antibody (ARG52262).