ARG63229
anti-ELF3 / ERT / ESX antibody
anti-ELF3 / ERT / ESX antibody for Western blot and Human
Gene Regulation antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes ELF3 / ERT / ESX |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ELF3 / ERT / ESX |
| Antigen Species | Human |
| Immunogen | C-SGWKEEEVLQSRN |
| Conjugation | Un-conjugated |
| Alternate Names | ERT; Epithelium-specific Ets transcription factor 1; Epithelial-restricted with serine box; ESE-1; ESX; E74-like factor 3; EPR-1; Epithelium-restricted Ets protein ESX; ETS-related transcription factor Elf-3 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by antigen affinity chromatography. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P78545 Human ETS-related transcription factor Elf-3 |
|---|---|
| Gene Symbol | ELF3 |
| Gene Full Name | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| Function | Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development (By similarity). [UniProt] |
| Research Area | Gene Regulation antibody |
| Calculated MW | 41 kDa |
Images (2) Click the Picture to Zoom In
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ARG63229 anti-ELF3 / ERT / ESX antibody WB image
Western blot: NCI-H460 lysate (RIPA buffer, 30µg total protein per lane) stained with ARG63229 anti-ELF3 / ERT / ESX antibody at 3 µg/ml dilution.
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ARG63229 anti-ELF3 / ERT / ESX antibody WB image
Western blot: 1). Mock transfection; 2) ELF3 (RC200631) expressing plasmid transfected HEK293 cell lysate standed with ARG63229 anti-ELF3 / ERT / ESX antibody.
