ARG63261

anti-EVC2 / Limbin antibody

anti-EVC2 / Limbin antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Cell Biology and Cellular Response antibody

Overview

Product Description Goat Polyclonal antibody recognizes EVC2 / Limbin
Tested Reactivity Hu
Tested Application IHC-P, WB
Specificity This antibody is expected to recognise isoform 1 (NP_667338.3) and isoform 2 (NP_001159608.1).
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name EVC2 / Limbin
Antigen Species Human
Immunogen C-LNAKKAMRALGMD
Conjugation Un-conjugated
Alternate Names Ellis-van Creveld syndrome protein 2; WAD; Limbin; EVC2; LBN

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P2 - 4 µg/ml
WB0.5 µg/ml
Application Note IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by antigen affinity chromatography.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 132884 Human EVC2

Swiss-port # Q86UK5 Human Limbin

Background This gene encodes a protein that functions in bone formation and skeletal development. Mutations in this gene, as well as in a neighboring gene that lies in a head-to-head configuration, cause Ellis-van Creveld syndrome, an autosomal recessive skeletal dysplasia that is also known as chondroectodermal dysplasia. Mutations in this gene also cause acrofacial dysostosis Weyers type, also referred to as Curry-Hall syndrome, a disease that combines limb and facial abnormalities. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Research Area Cell Biology and Cellular Response antibody
Calculated MW 148 kDa

Images (1) Click the Picture to Zoom In

  • ARG63261 anti-EVC2 / Limbin antibody IHC-P image

    Immunohistochemistry: paraffin embedded Human Placenta. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63261 anti-EVC2 / Limbin antibody at 2 µg/ml dilution followed by HRP-staining.