ARG45456
anti-F11 antibody
anti-F11 antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes F11 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | F11 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human F11. |
| Conjugation | Un-conjugated |
| Alternate Names | F11; Coagulation Factor XI; FXI; Plasma Thromboplastin Antecedent; PTA; Coagualtion Factor XI; EC 3.4.21.27; EC 3.4.21 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 150 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | F11 |
| Gene Full Name | Coagulation Factor XI |
| Background | This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq, Jul 2008] |
| Function | Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX. [UniProt] |
| Cellular Localization | Secreted. [UniProt] |
| Calculated MW | 70 kDa |
| PTM | Disulfide bond; Glycoprotein; Zymogen. [UniProt] |
Images (5) Click the Picture to Zoom In
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ARG45456 anti-F11 antibody ICC/IF image
Immunofluorescence: SiHa stained with ARG45456 anti-F11 antibody at 5 μg/ml dilution.
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ARG45456 anti-F11 antibody WB image
Western blot: HCCP stained with ARG45456 anti-F11 antibody at 0.25 μg/ml dilution.
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ARG45456 anti-F11 antibody FACS image
Flow Cytometry: HepG2 stained with ARG45456 anti-F11 antibody at 1 µg/10^6 cells dilution.
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ARG45456 anti-F11 antibody WB image
Western blot: Rat liver stained with ARG45456 anti-F11 antibody at 0.25 μg/ml dilution.
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ARG45456 anti-F11 antibody WB image
Western blot: Mouse liver stained with ARG45456 anti-F11 antibody at 0.25 μg/ml dilution.
