ARG46151
anti-FAF1 antibody
anti-FAF1 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes FAF1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | FAF1 |
| Antigen Species | Human |
| Immunogen | A 19 amino acid synthetic peptide within the last 50 amino acids of human FAF1. |
| Conjugation | Un-conjugated |
| Alternate Names | FAF1; UBX domain-containing protein 12; CGI-03; FAS-associated factor 1; HFAF1s; UBXD12; UBX domain-containing protein 3A; hFAF1; UBXN3A |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 80 kDa |
Properties
| Purification | Affinity chromatography purified |
|---|---|
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | FAF1 |
| Gene Full Name | Fas (TNFRSF6) associated factor 1 |
| Background | FAF1 (Fas-associated protein factor 1) specifically interacts with the cytoplasmic domain of wild type, but not mutated, Fas in both yeast and mammalian cells. When transiently expressed in T cells, FAF1 potentiates Fas-induced apoptosis. In contrast to TRADD, FADD, and RIP, FAF1 lacks a DDH (Death domain homologous region) and cannot induce apoptosis independent of Fas activation. |
| Function | Potentiates but cannot initiate FAS-induced apoptosis. [UniProt] |
| Calculated MW | 74 kDa |
Images (2) Click the Picture to Zoom In
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ARG46151 anti-FAF1 antibody IHC-P image
Immunohistochemistry: Rat spleen stained with ARG46151 anti-FAF1 antibody.
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ARG46151 anti-FAF1 antibody WB image
Western blot: THP-1 stained with ARG46151 anti-FAF1 antibody.
