ARG67249
anti-FOLR1 antibody [SQab30367]
anti-FOLR1 antibody [SQab30367] for IHC-Formalin-fixed paraffin-embedded sections and Human
. [Uniprot]
Overview
| Product Description | Rabbit Monoclonal antibody [SQab30367] recognizes FOLR1 . |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | SQab30367 |
| Isotype | IgG |
| Target Name | FOLR1 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to Human FOLR1. |
| Conjugation | Un-conjugated |
| Alternate Names | FOLR1; Folate Receptor Alpha; FOLR; Ovarian Tumor-Associated Antigen MOv18; Adult Folate-Binding Protein; Folate Receptor 1 (Adult); Folate Receptor, Adult; Folate Receptor 1; KB Cells FBP; FR-Alpha; FBP; Folate Binding Protein; FRalpha; NCFTD; FRα; FRA |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| Preservative | 0.01% Sodium azide |
| Stabilizer | 40% Glycerol and 0.05% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | FOLR1 |
| Gene Full Name | Folate Receptor Alpha |
| Background | The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2009] |
| Function | Required for normal embryonic development and normal cell proliferation. [Uniprot] |
| Cellular Localization | Cell membrane, Cytoplasmic vesicle, Endosome, Membrane, Secreted. [Uniprot] |
| Highlight | . [Uniprot] |
| Research Area | . [Uniprot] |
| Calculated MW | 30 kDa |
| PTM | Disulfide bond, Glycoprotein, GPI-anchor, Lipoprotein. [Uniprot] |
Images (1) Click the Picture to Zoom In
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ARG67249 anti-FOLR1 antibody [SQab30367] IHC-P image
Immunohistochemistry: Human Ovarian Cancer stained with ARG67249 anti-FOLR1 antibody [SQab30367] at 1:100 dilution.
