anti-FOX1 antibody [1G10]
anti-FOX1 antibody [1G10] for Western blot,ICC/IF and Bovine,Human,Mouse,Rat
Developmental Biology antibody; Gene Regulation antibody; Neuroscience antibody
|Product Description||Mouse Monoclonal antibody [1G10] recognizes FOX1|
|Tested Reactivity||Hu, Ms, Rat, Bov|
|Tested Application||ICC/IF, WB|
|Immunogen||Recombinant protein taken from the N-terminus of human FOX1 expressed in and purified from E. Coli|
|Alternate Names||RNA binding protein fox-1 homolog 1; HRNBP1; Ataxin-2-binding protein 1; Hexaribonucleotide-binding protein 1; 2BP1; FOX-1; FOX1; Fox-1 homolog A; A2BP1|
|Application Note||Specific for the ~46/48k FOX1 protein doublet.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
|Buffer||PBS and 10 mM Sodium azide|
|Preservative||10 mM Sodium azide|
|Storage Instruction||For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.|
|Note||For laboratory research only, not for drug, diagnostic or other use.|
|Gene Full Name||RNA binding protein, fox-1 homolog (C. elegans) 1|
|Background||FOX1, also known as ataxin-2 binding protein 1 (A2BP1), is a neuron specific RNA-binding protein that has been shown to regulate a wide range of alternative splicing events implicated in neuronal development and maturation including transcription factors and synaptic proteins (Fogel et al., 2012). Defects in FOX1 have also been associated with autism (Martin et al., 2007), attention-deficit hyperactivity disorder (Elia et al., 2010) and schizophrenia (Xu et al., 2008).|
|Research Area||Developmental Biology antibody; Gene Regulation antibody; Neuroscience antibody|
|Calculated MW||43 kDa|
Images (2) Click the Picture to Zoom In
ARG52282 anti-FOX1 antibody [1G10] WB image
Western Blot: rat cortex lysate showing specific immunolabeling of the ~46/48k FOX1 protein stained with ARG52282 FOX1 antibody [1G10] .
ARG52282 anti-FOX1 antibody [1G10] ICC/IF image
Immunofluorescence: cultured rat neurons stained with ARG52282 anti-FOX1 antibody [1G10] showing nuclear and distal cytoplasmic staining of FOX1 in green.