ARG46166
anti-FREM1 antibody
anti-FREM1 antibody for Western blot,ICC/IF and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes FREM1 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | FREM1 |
| Antigen Species | Human |
| Immunogen | A 15 amino acid synthetic peptide within the last 50 amino acids of human FREM1. |
| Conjugation | Un-conjugated |
| Alternate Names | FRAS1 related extracellular matrix 1; FREM1; BNAR; MOTA; TILRR; TRIGNO2; C9orf143; C9orf145; C9orf154; FRAS1-related extracellular matrix protein 1; Protein QBRICK |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -216°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q5H8C1 Human FRAS1-related extracellular matrix protein 1 Swiss-port # Q684R7 Mouse FRAS1-related extracellular matrix protein 1 |
|---|---|
| Gene Symbol | FREM1 |
| Gene Full Name | FRAS1 related extracellular matrix 1 |
| Background | This gene encodes a basement membrane protein that may play a role in craniofacial and renal development. Mutations in this gene have been associated with bifid nose with or without anorectal and renal anomalies. Alternatively spliced transcript variants encoding different isoforms have been described. PubMed ID 19940113 describes one such variant that initiates transcription within a distinct, internal exon; the resulting shorter isoform (named Toll-like/interleukin-1 receptor regulator, TILRR) is suggested to be a co-receptor of the interleukin 1 receptor family and may regulate receptor function and Toll-like receptor/interleukin 1 receptor signal transduction, contributing to the control of inflammatory response activation. [provided by RefSeq, Apr 2011] |
| Function | Extracellular matrix protein that plays a role in epidermal differentiation and is required for epidermal adhesion during embryonic development. [UniProt] |
| Cellular Localization | Extracellular matrix. [UniProt] |
| Calculated MW | 244 kDa |
| PTM | Disulfide bond; Glycoprotein. [UniProt] |
