ARG46787
anti-FTCD / 58K Golgi protein antibody
anti-FTCD / 58K Golgi protein antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Overview
| Product Description | Goat Polyclonal antibody recognizes FTCD / 58K Golgi protein |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | ICC/IF, IHC-P, WB |
| Specificity | Detects a band of 55-60 kDa by Western blot in the following human and mouse whole cell lysates. |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | FTCD / 58K Golgi protein |
| Antigen Species | Human |
| Immunogen | Purified recombinant peptide derived from within residues 50 aa to the N-terminus of human FTCD / 58K Golgi protein produced in E. coli. |
| Conjugation | Un-conjugated |
| Alternate Names | EC 2.1.2.5; LCHC1; Formiminotetrahydrofolate cyclodeaminase; Formimidoyltransferase-cyclodeaminase; Formiminotransferase-cyclodeaminase; Glutamate formiminotransferase; Glutamate formyltransferase; FTCD; EC 4.3.1.4 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 55-60 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Epitope affinity purified |
| Buffer | PBS, 0.05% Sodium azide and 20% Glycerol. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 20% Glycerol |
| Concentration | 3 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O95954 Human Formimidoyltransferase-cyclodeaminase Swiss-port # Q91XD4 Mouse Formimidoyltransferase-cyclodeaminase |
|---|---|
| Gene Symbol | FTCD |
| Gene Full Name | formimidoyltransferase cyclodeaminase |
| Background | The protein encoded by this gene is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Mutations in this gene are associated with glutamate formiminotransferase deficiency. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Dec 2009] |
| Function | Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool. Binds and promotes bundling of vimentin filaments originating from the Golgi. [UniProt] |
| Cellular Localization | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Golgi apparatus. Note=More abundantly located around the mother centriole. [UniProt] |
Images (10) Click the Picture to Zoom In
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ARG46787 anti-FTCD / 58K Golgi protein antibody IHC-P image
Immunohistochemistry: Human pancreas stained with ARG46787 anti-FTCD / 58K Golgi protein antibody at 1:750 dilution.
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ARG46787 anti-FTCD / 58K Golgi protein antibody IHC-P image
Immunohistochemistry: Human skin stained with ARG46787 anti-FTCD / 58K Golgi protein antibody at 1:750 dilution.
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ARG46787 anti-FTCD / 58K Golgi protein antibody WB image
Western blot: ARPE19, Hepa-6 stained with ARG46787 anti-FTCD / 58K Golgi protein antibody at 1:1000 dilution.
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ARG46787 anti-FTCD / 58K Golgi protein antibody IHC-P image
Immunohistochemistry: Mouse kidney stained with ARG46787 anti-FTCD / 58K Golgi protein antibody at 1:750 dilution.
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ARG46787 anti-FTCD / 58K Golgi protein antibody IHC-P image
Immunohistochemistry: Mouse liver stained with ARG46787 anti-FTCD / 58K Golgi protein antibody at 1:750 dilution.
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ARG46787 anti-FTCD / 58K Golgi protein antibody IHC-P image
Immunohistochemistry: Mouse testis stained with ARG46787 anti-FTCD / 58K Golgi protein antibody at 1:750 dilution.
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ARG46787 anti-FTCD / 58K Golgi protein antibody ICC/IF image
Immunofluorescence: 3T3 stained with ARG46787 anti-FTCD / 58K Golgi protein antibody at 1:100 dilution.
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ARG46787 anti-FTCD / 58K Golgi protein antibody ICC/IF image
Immunofluorescence: 3T3 stained with ARG46787 anti-FTCD / 58K Golgi protein antibody at 1:100 dilution.
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ARG46787 anti-FTCD / 58K Golgi protein antibody ICC/IF image
Immunofluorescence: NHI/3T3 stained with ARG46787 anti-FTCD / 58K Golgi protein antibody at 1:100 dilution.
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ARG46787 anti-FTCD / 58K Golgi protein antibody ICC/IF image
Immunofluorescence: NHI/3T3 stained with ARG46787 anti-FTCD / 58K Golgi protein antibody at 1:100 dilution.
