ARG46172
anti-Fatso antibody
anti-Fatso antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Fatso |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Fatso |
| Antigen Species | Human |
| Immunogen | A 15 amino acid synthetic peptide within the first 50 amino acids of human Fatso. |
| Conjugation | Un-conjugated |
| Alternate Names | FTO; EC 1.14.11.-; Alpha-ketoglutarate-dependent dioxygenase FTO; Fat mass and obesity-associated protein; ALKBH9 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Purification | Affinity chromatography purified |
|---|---|
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9C0B1 Human Alpha-ketoglutarate-dependent dioxygenase FTO |
|---|---|
| Gene Symbol | FTO |
| Gene Full Name | fat mass and obesity associated |
| Background | The FTO gene is the most robust gene for common obesity characterized to date. FTO gene expression has been found to be significantly upregulated in the hypothalamus of rats after food deprivation and strongly negatively correlated with the expression of orexin peptide which is involved in the stimulation of food intake (Fredricksson R et al., 2008). Deletion analysis of FTO gene in mice showed that Fto is functionally involved in the control of both energy intake and energy expenditure (Fischer J et al., 2009) |
| Calculated MW | 58 kDa |
Images (3) Click the Picture to Zoom In
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ARG46172 anti-Fatso antibody IHC-P image
Immunohistochemistry: Mouse brain stained with ARG46172 anti-Fatso antibody.
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ARG46172 anti-Fatso antibody ICC/IF image
Immunofluorescence: Mouse Brain stained with ARG46172 anti-Fatso antibody.
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ARG46172 anti-Fatso antibody WB image
Western blot: Human uterus stained with ARG46172 anti-Fatso antibody.
