anti-G-CSF Receptor antibody [S-1284]
anti-G-CSF Receptor antibody [S-1284] for Western blot and Human
Cancer antibody; Developmental Biology antibody; Immune System antibody
|Product Description||Mouse Monoclonal antibody [S-1284] recognizes G-CSF Receptor|
|Target Name||G-CSF Receptor|
|Immunogen||Purified recombinant MBP-GCSFR fusion protein|
|Full Name||colony stimulating factor 3 receptor (granulocyte)|
|Alternate Names||G-CSF receptor; CD114; CD antigen CD114; G-CSF-R; GCSFR; Granulocyte colony-stimulating factor receptor|
|Application Note||Western Blot: The antibody, when used at concentration of 1-10μg/mL will allow visualization of 250 ng/lane of human G-CSFR-MBP.
The antibody recognizes denatured G-CSFR in Western blot following SDS-PAGE. Suggest use 200μg of cell lysate or immunoprecipitated protein.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
|Purification||Protein G affinity purified|
|Buffer||0.01M PBS (pH 7.2)|
|Storage instruction||For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.|
|Note||For laboratory research only, not for drug, diagnostic or other use.|
|Gene Full Name||colony stimulating factor 3 receptor (granulocyte)|
|Background||The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. [provided by RefSeq, Aug 2010]|
|Function||Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differientation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface. [UniProt]|
|Research Area||Cancer antibody; Developmental Biology antibody; Immune System antibody|