ARG22235

anti-GABAA Receptor delta antibody [S151-3]

anti-GABAA Receptor delta antibody [S151-3] for Western blot,ICC/IF and Human,Mouse,Rat

Overview

Product Description Mouse Monoclonal antibody [S151-3] recognizes GABAA Receptor delta
Tested Reactivity Hu, Ms, Rat
Tested Application ICC/IF, WB
Specificity Detects ~55kDa.
Host Mouse
Clonality Monoclonal
Clone S151-3
Isotype IgG2a
Target Name GABAA Receptor delta
Antigen Species Rat
Immunogen Synthetic peptide around aa. 15-34 of Rat GABAA Receptor delta
Conjugation Un-conjugated
Alternate Names A; EJM7; GEFSP5; Gamma-aminobutyric acid receptor subunit delta; EIG10; GABA

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:100
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purification with Protein G.
Buffer PBS (pH 7.4), 0.09% Sodium azide and 50% Glycerol
Preservative 0.09% Sodium azide
Stabilizer 50% Glycerol
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 14403 Mouse GABRD

GeneID: 2563 Human GABRD

GeneID: 29689 Rat GABRD

Gene Symbol Gabrd
Gene Full Name gamma-aminobutyric acid (GABA) A receptor, delta
Background Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Function GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. [UniProt]
Cellular Localization Cell Junction, Cell membrane, postsynaptic cell membrane, Synapse
Calculated MW 51 kDa

Images (1) Click the Picture to Zoom In

  • ARG22235 anti-GABAA Receptor delta antibody [S151-3] WB image

    Western blot: Rat cell line lysates stained with ARG22235 anti-GABAA Receptor delta antibody [S151-3] at 1:1000 dilution.