anti-GABAB Receptor 1 phospho (Ser923) antibody

anti-GABAB Receptor 1 phospho (Ser923) antibody for Western blot and Rat

Neuroscience antibody


Product Description Rabbit Polyclonal antibody recognizes GABAB Receptor 1 phospho (Ser923)
Tested Reactivity Rat
Predict Reactivity Hu, Ms, Bov, NHuPrm
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name GABAB Receptor 1
Antigen Species Rat
Immunogen Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser923 conjugated to KLH
Conjugation Un-conjugated
Alternate Names Gb1; GABA-B-R1; GABA-B receptor 1; GABA-BR1; GPRC3A; GABBR1-3; dJ271M21.1.2; dJ271M21.1.1; GABABR1; Gamma-aminobutyric acid type B receptor subunit 1; GB1

Application Instructions

Application Suggestion
Tested Application Dilution
Application Note Specific for ~102k GABAB R1 phosphorylated at Ser923. Immunolabeling of the GABAB R1 band is completely blocked by λ-phosphatase treatment.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Purification Affinity Purified
Buffer 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol
Stabilizer 0.1 mg/ml BSA, 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 81657 Rat GABBR1

Swiss-port # Q9Z0U4 Rat Gamma-aminobutyric acid type B receptor subunit 1

Gene Symbol GABBR1
Gene Full Name gamma-aminobutyric acid (GABA) B receptor 1
Background Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABAA and the GABAB subtype of receptors. GABAB receptors are heterodimeric G protein-coupled receptors that mediate slow synaptic inhibition in the central nervous system. Phosphorylation enhances GABAB receptor effector coupling (Couve et al., 2004). Phosphorylation of Ser923 is thought to be important in the regulation of GABAB receptor function.
Research Area Neuroscience antibody
Calculated MW 108 kDa

Images (1) Click the Picture to Zoom In

  • ARG52306 anti-GABAB Receptor 1 phospho (Ser923) antibody WB image

    Western blot: Rat synaptic membrane showing specific immunolabeling of the ~102 kDa GABAB R1 protein phosphorylated at Ser923 (control) stained with ARG52306 anti-GABAB Receptor 1 phospho (Ser923) antibody. The phosphospecificity of this labeling is shown in the second lane (lambda-phosphatase: lambda-Ptase). The blot is identical to the control except that it was incubated in lambda-Ptase (1200 units for 30 min) before being exposed to the phospho-Ser923 GABAB antibody. The immunolabeling is completely eliminated by treatment with lambda-Ptase.