ARG45470
anti-GANAB antibody
anti-GANAB antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes GANAB |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GANAB |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human GANAB. |
| Conjugation | Un-conjugated |
| Alternate Names | GANAB; Glucosidase II Alpha Subunit; G2AN; Neutral Alpha-Glucosidase AB; KIAA0088; GIIalpha; GluII; GIIA; Alpha-Glucosidase 2; Glucosidase, Alpha; Neutral AB; Glucosidase II Subunit Alpha; EC 3.2.1.207; EC 3.2.1.84 47; EC 3.2.1 47; PKD3 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Observed Size | 100 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | GANAB |
| Gene Full Name | Glucosidase II Alpha Subunit |
| Background | This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease. [provided by RefSeq, Jul 2016] |
| Function | Catalytic subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc2Man9GlcNAc2 oligosaccharide precursor of immature glycoproteins. [UniProt] |
| Cellular Localization | Endoplasmic reticulum; Golgi apparatus. [UniProt] |
| Calculated MW | 107 kDa |
| PTM | Disulfide bond; Glycoprotein; Phosphoprotein. [UniProt] |
Images (6) Click the Picture to Zoom In
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ARG45470 anti-GANAB antibody IHC-P image
Immunohistochemistry: Human placenta stained with ARG45470 anti-GANAB antibody at 2 μg/ml dilution.
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ARG45470 anti-GANAB antibody ICC/IF image
Immunofluorescence: Hela stained with ARG45470 anti-GANAB antibody at 5 μg/ml dilution.
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ARG45470 anti-GANAB antibody WB image
Western blot: Human placenta stained with ARG45470 anti-GANAB antibody at 0.5 μg/ml dilution.
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ARG45470 anti-GANAB antibody FACS image
Flow Cytometry: SH-SY5Y stained with ARG45470 anti-GANAB antibody at 1 µg/10^6 cells dilution.
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ARG45470 anti-GANAB antibody WB image
Western blot: Rat kidney stained with ARG45470 anti-GANAB antibody at 0.5 μg/ml dilution.
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ARG45470 anti-GANAB antibody WB image
Western blot: Mouse kidney stained with ARG45470 anti-GANAB antibody at 0.5 μg/ml dilution.
