anti-GAT2 / GABA Transporter 2 antibody

anti-GAT2 / GABA Transporter 2 antibody for Immunohistochemistry and Rat

Neuroscience antibody


Product Description

Rabbit Polyclonal antibody recognizes GAT2/GABA Transporter2

Tested Reactivity Rat
Predict Reactivity Ms
Tested Application IHC
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name GAT2 / GABA Transporter 2
Antigen Species Rat
Immunogen Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH
Conjugation Un-conjugated
Alternate Names GAT-2; Solute carrier family 6 member 13; Sodium- and chloride-dependent GABA transporter 2; GAT2; GAT3

Application Instructions

Application Suggestion
Tested Application Dilution
Application Note Specific for the ~82k GAT-2 protein.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Purification Affinity Purified
Buffer 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol
Stabilizer 0.1 mg/ml BSA, 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 171163 Rat SLC6A13

Swiss-port # P31646 Rat Sodium- and chloride-dependent GABA transporter 2

Gene Symbol SLC6A13
Gene Full Name solute carrier family 6 (neurotransmitter transporter), member 13
Background Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl− channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by highaffinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-2 is found in a wide range of neuronal and non-neuronal cells including dendrites and axon terminals as well as epithelial cells and cells forming the pia and arachnoid complex (Conti et al., 1999).
Research Area Neuroscience antibody
Calculated MW 68 kDa