anti-GAT2 / GABA Transporter 2 antibody
anti-GAT2 / GABA Transporter 2 antibody for Immunohistochemistry and Rat
Rabbit Polyclonal antibody recognizes GAT2/GABA Transporter2
|Target Name||GAT2 / GABA Transporter 2|
|Immunogen||Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH|
|Alternate Names||GAT-2; Solute carrier family 6 member 13; Sodium- and chloride-dependent GABA transporter 2; GAT2; GAT3|
|Application Note||Specific for the ~82k GAT-2 protein.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
|Buffer||10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol|
|Stabilizer||0.1 mg/ml BSA, 50% Glycerol|
|Storage Instruction||For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.|
|Note||For laboratory research only, not for drug, diagnostic or other use.|
|Gene Full Name||solute carrier family 6 (neurotransmitter transporter), member 13|
|Background||Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl− channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by highaffinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-2 is found in a wide range of neuronal and non-neuronal cells including dendrites and axon terminals as well as epithelial cells and cells forming the pia and arachnoid complex (Conti et al., 1999).|
|Research Area||Neuroscience antibody|
|Calculated MW||68 kDa|