ARG67034

anti-GATA3 antibody [SQab30328]

anti-GATA3 antibody [SQab30328] for IHC-Formalin-fixed paraffin-embedded sections and Human

Overview

Product Description Recombinant rabbit Monoclonal antibody [SQab30328] recognizes GATA3
Tested Reactivity Hu
Tested Application IHC-P
Host Rabbit
Clonality Monoclonal
Clone SQab30328
Isotype IgG
Target Name GATA3
Antigen Species Human
Immunogen Synthetic peptide of Human GATA3
Conjugation Un-conjugated
Protein Full Name Trans-acting T-cell-specific transcription factor GATA-3
Alternate Names GATA3, GATA Binding Protein 3, HDR, Trans-Acting T-Cell-Specific Transcription Factor GATA-3, GATA-Binding Factor 3, GATA-Binding Protein 3, HDRS

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:50 - 1:100
Application Note IHC-P: Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0). Incubate the samples at RT (18-25°C) for 44 min.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Ductal carcinoma

Properties

Form Liquid
Purification Purification with Protein A.
Buffer PBS, 0.01% Sodium azide, 40% Glycerol and 0.05%BSA.
Preservative 0.01% Sodium azide
Stabilizer 40% Glycerol and 0.05%BSA
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Symbol GATA3
Gene Full Name GATA Binding Protein 3
Background This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. [provided by RefSeq, Nov 2009]
Function Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. Positively regulates ASB2 expression. [UniProt]
Cellular Localization Nucleus
Calculated MW 48 kDa
PTM Phosphoprotein [UniProt]

Images (1) Click the Picture to Zoom In

  • ARG67034 anti-GATA3 antibody [SQab30328] IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded ductal carcinoma human breast tissue stained with ARG67034 anti-GATA3 antibody [SQab30328].