ARG46176
anti-GDF1 antibody
anti-GDF1 antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes GDF1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GDF1 |
| Antigen Species | Human |
| Immunogen | A 16 amino acid synthetic peptide within aa. 30 - 80 of human GDF1. |
| Conjugation | Un-conjugated |
| Alternate Names | growth differentiation factor 1; GDF1; RAI; DORV; DTGA3GDF-1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -226°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P20863 Mouse Embryonic growth/differentiation factor 1 Swiss-port # P27539 Human Embryonic growth/differentiation factor 1 |
|---|---|
| Gene Symbol | GDF1 |
| Gene Full Name | growth differentiation factor 1 |
| Background | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. Studies in rodents suggest that this protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis. The encoded protein is translated from a bicistronic mRNA that also encodes ceramide synthase 1. Mutations in this gene are associated with several congenital cardiovascular malformations. [provided by RefSeq, Jul 2016] |
| Function | May mediate cell differentiation events during embryonic development. [UniProt] |
| Cellular Localization | Secreted. [UniProt] |
| Calculated MW | 39 kDa |
| PTM | Disulfide bond; Glycoprotein. [UniProt] |
