ARG46177
anti-GDPD5 / GDE2 antibody
anti-GDPD5 / GDE2 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes GDPD5 / GDE2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GDPD5 / GDE2 |
| Antigen Species | Human |
| Immunogen | A 18 amino acid synthetic peptide within the first 50 amino acids of human GDPD5 / GDE2. |
| Conjugation | Un-conjugated |
| Alternate Names | GDPD5; PP1665; Glycerophosphodiester phosphodiesterase domain-containing protein 5; Glycerophosphodiester phosphodiesterase 2; GDE2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 52 kDa |
Properties
| Purification | Affinity chromatography purified |
|---|---|
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q640M6 Mouse Glycerophosphodiester phosphodiesterase domain-containing protein 5 Swiss-port # Q8WTR4 Human Glycerophosphodiester phosphodiesterase domain-containing protein 5 |
|---|---|
| Gene Symbol | GDPD5 |
| Gene Full Name | glycerophosphodiester phosphodiesterase domain containing 5 |
| Background | Glycerophosphodiester phosphodiesterases (GDPDs; EC 3.1.4.46), such as GDPD5, are involved in glycerol metabolism (Lang et al., 2008 [PubMed 17578682]).[supplied by OMIM, Jan 2010] |
| Function | Glycerophosphodiester phosphodiesterase that promotes neurite formation and drives spinal motor neuron differentiation (By similarity). Mediates the cleavage of glycosylphosphatidylinositol (GPI) anchor of target proteins: removes the GPI-anchor of RECK, leading to release RECK from the plasma membrane (By similarity). May contribute to the osmotic regulation of cellular glycerophosphocholine (By similarity). [UniProt] |
| Cellular Localization | Endomembrane system; Multi-pass membrane protein. Cytoplasm, perinuclear region. Cell projection, growth cone. Note=In a punctate perinuclear pattern. [UniProt] |
| Calculated MW | 40,67 kDa |
| PTM | Intramolecular disulfide bond between Cys-25 and Cys-571 is reduced by PRDX1. [UniProt] |
Images (2) Click the Picture to Zoom In
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ARG46177 anti-GDPD5 / GDE2 antibody IHC-P image
Immunohistochemistry: Human kidney stained with ARG46177 anti-GDPD5 / GDE2 antibody.
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ARG46177 anti-GDPD5 / GDE2 antibody WB image
Western blot: Mouse kidney stained with ARG46177 anti-GDPD5 / GDE2 antibody.
