ARG45545
anti-GFPT1 antibody
anti-GFPT1 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes GFPT1 |
|---|---|
| Tested Reactivity | Hu, Rat |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GFPT1 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to C-terminal region of human GFPT1. |
| Conjugation | Un-conjugated |
| Alternate Names | GFPT1; Glutamine--Fructose-6-Phosphate Transaminase 1; GFAT1; GFAT; GFPT; GFA; Glutamine--Fructose-6-Phosphate Aminotransferase [Isomerizing] 1; Glutamine:Fructose-6-Phosphate Amidotransferase 1; D-Fructose-6-Phosphate Amidotransferase 1; Hexosephosphate Aminotransferase 1; EC 2.6.1.16; GFAT 1; Glucosamine--Fructose-6-Phosphate Aminotransferase [Isomerizing] 1; Glutamine-Fructose-6-Phosphate Transaminase 1; CMSTA1; GFAT1m; GFPT1L; CMS12; MSLG |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Observed Size | 79 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P82808 Rat Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 Swiss-port # Q06210 Human Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 |
|---|---|
| Gene Symbol | GFPT1 |
| Gene Full Name | Glutamine--Fructose-6-Phosphate Transaminase 1 |
| Background | This gene encodes the first and rate-limiting enzyme of the hexosamine pathway and controls the flux of glucose into the hexosamine pathway. The product of this gene catalyzes the formation of glucosamine 6-phosphate. [provided by RefSeq, Sep 2008] |
| Function | Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins. Regulates the circadian expression of clock genes BMAL1 and CRY1 (By similarity). Has a role in fine tuning the metabolic fluctuations of cytosolic UDP-GlcNAc and its effects on hyaluronan synthesis that occur during tissue remodeling . [UniProt] |
| Cellular Localization | Cytosol. [UniProt] |
| Calculated MW | 79 kDa |
| PTM | Phosphoprotein. [UniProt] |
Images (4) Click the Picture to Zoom In
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ARG45545 anti-GFPT1 antibody IHC-P image
Immunohistochemistry: Human colon adenocarcinoma stained with ARG45545 anti-GFPT1 antibody at 2 μg/ml dilution.
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ARG45545 anti-GFPT1 antibody ICC/IF image
Immunofluorescence: CACO-2 stained with ARG45545 anti-GFPT1 antibody at 5 μg/ml dilution.
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ARG45545 anti-GFPT1 antibody WB image
Western blot: HepG2 stained with ARG45545 anti-GFPT1 antibody at 0.5 μg/ml dilution.
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ARG45545 anti-GFPT1 antibody FACS image
Flow Cytometry: CACO-2 stained with ARG45545 anti-GFPT1 antibody at 1 µg/10^6 cells dilution.
