ARG47073
anti-GGA1 antibody
anti-GGA1 antibody for Western blot and Human,Mouse
Overview
| Product Description | Mouse Polyclonal antibody recognizes GGA1 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | WB |
| Host | Mouse |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GGA1 |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human GGA1. |
| Conjugation | Un-conjugated |
| Alternate Names | GGA1; ADP-ribosylation factor-binding protein GGA1; Gamma-adaptin-related protein 1; Golgi-localized; gamma ear-containing; ARF-binding protein 1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS, 0.09% Sodium azide, 50% Glycerol and 0.5% BSA |
| Preservative | 0.09% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8R0H9 Mouse ADP-ribosylation factor-binding protein GGA1 Swiss-port # Q9UJY5 Human ADP-ribosylation factor-binding protein GGA1 |
|---|---|
| Gene Symbol | GGA1 |
| Gene Full Name | golgi associated, gamma adaptin ear containing, ARF binding protein 1 |
| Background | This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Function | Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (DXXLL) motif. [UniProt] |
| Cellular Localization | Golgi apparatus; Membrane; Endosome. [UniProt] |
| Calculated MW | 70 kDa |
| PTM | Acetylation; Phosphoprotein; Ubl conjugation. [UniProt] |
