ARG10371

anti-GPBB + GPMM antibody [17B6]

anti-GPBB + GPMM antibody [17B6] for Purification,Western blot and Human

Overview

Product Description Mouse Monoclonal antibody [17B6] recognizes GPBB + GPMM
Tested Reactivity Hu
Tested Application Puri, WB
Specificity This antibody recognizes BB and MM isoenzymes.
Host Mouse
Clonality Monoclonal
Clone 17B6
Isotype IgG1
Target Name GPBB + GPMM
Antigen Species Human
Immunogen Human GPBB.
Conjugation Un-conjugated
Alternate Names GPBB; EC 2.4.1.1; Glycogen phosphorylase, brain form

Application Instructions

Application Suggestion
Application Dilution
PuriAssay-dependent
WBAssay-dependent
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purification with Protein A.
Buffer PBS (pH 7.4) and 0.1% Sodium azide
Preservative 0.1% Sodium azide
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 5834 Human PYGB

Swiss-port # P11216 Human Glycogen phosphorylase, brain form

Gene Symbol PYGB
Gene Full Name phosphorylase, glycogen; brain
Background The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation. [provided by RefSeq, Jul 2008]
Function Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. [UniProt]
PTM Phosphorylated (PubMed:27402852). Phosphorylation of Ser-15 converts phosphorylase B (unphosphorylated) to phosphorylase A (By similarity).