ARG46188
anti-GPRASP1 antibody
anti-GPRASP1 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes GPRASP1 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GPRASP1 |
| Antigen Species | Human |
| Immunogen | A 15 amino acid synthetic peptide within aa. 260 - 310 of human GPRASP1. |
| Conjugation | Un-conjugated |
| Alternate Names | GPRASP1; G protein-coupled receptor associated sorting protein 1; G-protein coupled receptor-associated sorting protein 1; GASP; GASP-1; GASP1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 150 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -238°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q5JY77 Human G-protein coupled receptor-associated sorting protein 1 Swiss-port # Q5U4C1 Mouse G-protein coupled receptor-associated sorting protein 1 |
|---|---|
| Gene Symbol | GPRASP1 |
| Gene Full Name | G protein-coupled receptor associated sorting protein 1 |
| Background | This gene encodes a member of the GPRASP (G protein-coupled receptor associated sorting protein) family. The protein may modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. It targets receptors for degradation in lysosomes. The receptors interacting with this sorting protein include D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta-2 adrenergic receptor (ADRB2), D4 dopamine receptor (DRD4) and cannabinoid 1 receptor (CB1R). Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, May 2010] |
| Function | Modulates lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. Targets receptors for degradation in lysosomes via its interaction with BECN2. [UniProt] |
| Cellular Localization | Cytoplasm. [UniProt] |
| Calculated MW | 153 kDa |
| PTM | Phosphoprotein. [UniProt] |
