anti-GRASP antibody

anti-GRASP antibody for Western blot and Rat

Neuroscience antibody; Signaling Transduction antibody


Product Description Rabbit Polyclonal antibody recognizes GRASP
Tested Reactivity Rat
Predict Reactivity Hu, Ms, Bov, Dog
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name GRASP
Antigen Species Rat
Immunogen Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH
Conjugation Un-conjugated
Alternate Names GRASP-1; GRIP1-associated protein 1

Application Instructions

Application Suggestion
Tested Application Dilution
Application Note Specific for the ~95k GRASP protein.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Purification Affinity Purified
Buffer 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol
Stabilizer 0.1 mg/ml BSA, 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 116493 Rat GRIPAP1

Swiss-port # Q9JHZ4 Rat GRIP1-associated protein 1

Gene Symbol GRIPAP1
Gene Full Name GRIP1 associated protein 1
Background PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000). Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity (Ye et al., 2000).
Research Area Neuroscience antibody; Signaling Transduction antibody
Calculated MW 96 kDa
PTM Proteolytically cleaved by caspase-3.

Images (1) Click the Picture to Zoom In

  • ARG52323 anti-GRASP antibody WB image

    Western Blot: rate cerebellar lysate showing specific immunolabeling of the ~95k GRASP protein stained with GRASP antibody (ARG52323).