ARG46190
anti-GRIK5 antibody
anti-GRIK5 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes GRIK5 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GRIK5 |
| Antigen Species | Human |
| Immunogen | A 17 amino acid synthetic peptide within the last 50 amino acids of human GRIK5. |
| Conjugation | Un-conjugated |
| Alternate Names | GRIK5; GluK5; GRIK2 (Previous symbols); Glutamate receptor ionotropic, kainate 5; Excitatory amino acid receptor 2; KA2; EAA2; Glutamate receptor KA-2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Purification | Affinity chromatography purified |
|---|---|
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | GRIK5 |
| Gene Full Name | glutamate receptor, ionotropic, kainate 5 |
| Background | This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
| Function | Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds kainate > quisqualate > domoate > L-glutamate >> AMPA >> NMDA = 1S,3R-ACPD. [UniProt] |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. [UniProt] |
| Calculated MW | 109 kDa |
Images (3) Click the Picture to Zoom In
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ARG46190 anti-GRIK5 antibody IHC-P image
Immunohistochemistry: Human brain stained with ARG46190 anti-GRIK5 antibody.
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ARG46190 anti-GRIK5 antibody ICC/IF image
Immunofluorescence: Human brain stained with ARG46190 anti-GRIK5 antibody.
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ARG46190 anti-GRIK5 antibody WB image
Western blot: Human brain stained with ARG46190 anti-GRIK5 antibody.
