ARG67256
anti-GSDMD antibody
anti-GSDMD antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes GSDMD |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GSDMD |
| Antigen Species | Human |
| Immunogen | Synthesized peptide derived from Human GSDMD (a.a. sequence :1-100). |
| Conjugation | Un-conjugated |
| Alternate Names | GSDMD; Gasdermin D; GSDMDC1; DF5L; Gasdermin Domain-Containing Protein 1; Gasdermin Domain Containing 1; Gasdermin-D; FLJ12150; DFNA5L ; FKSG10 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 36 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS, 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | GSDMD |
| Gene Full Name | Gasdermin D |
| Background | Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009] |
| Function | Does not bind to unphosphorylated phosphatidylinositol, phosphatidylethanolamine nor phosphatidylcholine. [Uniprot] |
| Cellular Localization | Cell membrane, Cytoplasm, Inflammasome, Membrane, Mitochondrion, Nucleus, Secreted. [Uniprot] |
| Calculated MW | 53 kDa |
| PTM | Glycoprotein, Lipoprotein, Palmitate, Phosphoprotein, Ubl conjugation. [Uniprot] |
Images (1) Click the Picture to Zoom In
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ARG67256 anti-GSDMD antibody IHC-P image
Immunohistochemistry: Human hepatocellular carcinoma stained with ARG67256 anti-GSDMD antibody at 1:200 dilution.
