ARG20184

anti-HDAC7 antibody

anti-HDAC7 antibody for Immunohistochemistry,Immunoprecipitation,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes HDAC7
Tested Reactivity Hu, Ms, Rat
Tested Application IHC, IP, WB
Specificity The antibody detects ~105 kDa HDAC7. The antibody does not recognize other members of the HDAC family.
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name HDAC7
Immunogen Synthetic peptide surrounding amino acid 921 of murine HDAC7
Conjugation Un-conjugated
Full Name histone deacetylase 7
Alternate Names HD7; Histone deacetylase 7A; EC 3.5.1.98; Histone deacetylase 7; HD7a; HD7A; HDAC7A

Application Instructions

Application Suggestion
Tested Application Dilution
IHC20-40 µg/ml
IP20-40 µg/ml
WB0.5-4 µg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Mouse small intestine tissue lysate can be use as a positive control.
Calculated MW 103 kDa

Properties

Form Liquid
Purification Affinity Purified Antibody
Buffer PBS (pH 7.2), 30% Glycerol, 0.5% BSA and 0.01% Thimerosal
Preservative 0.01% Thimerosal
Stabilizer 30% Glycerol, 0.5% BSA
Concentration 0.2 mg/ml
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 51564 Human HDAC7

GeneID: 56233 Mouse HDAC7

Swiss-port # Q8C2B3 Mouse Histone deacetylase 7

Swiss-port # Q8WUI4 Human Histone deacetylase 7

Gene Symbol HDAC7
Gene Full Name histone deacetylase 7
Background Human HDAC7 is composed of 912 amino acid residues. Although HDAC7 is localized mostly to the cell nucleus, it is also found in the cytoplasm, suggesting nucleo-cytoplasmic shuttling. The histone deacetylase activity of HDAC7 maps to a carboxy-terminal domain and is dependent on interaction with class I HDACs in the nucleus. HDAC7 catalyzes removal of acetyl-groups from acetyl-lysines of histones and promotes compaction of chromatin in these regions, leading to the inhibition of gene transcription.

Images (1) Click the Picture to Zoom In

  • ARG20184 anti-HDAC7 antibody WB image

    Western Blot: Mouse small intestine tissue lysate stained with anti-HDAC7 antibody (ARG20184).

    The antibody detects ~105 kDa HDAC7. Mouse small intestine tissue lysate can be use as a positive control. The antibody does not recognize other members of the HDAC family.