anti-HDGF antibody

anti-HDGF antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections,ICC/IF and Human


Product Description Rabbit Polyclonal antibody recognizes HDGF
Tested Reactivity Hu
Tested Application ICC/IF, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name HDGF
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide corresponding to aa. 171-197 (C-terminus) of Human HDGF.
Conjugation Un-conjugated
Alternate Names HMG1L2; HMG-1L2; HDGF; High mobility group protein 1-like 2; Hepatoma-derived growth factor

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:10 - 1:50
IHC-P1:10 - 1:50
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control HeLa


Form Liquid
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Buffer PBS and 0.09% (W/V) Sodium azide.
Preservative 0.09% (W/V) Sodium azide.
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 3068 Human HDGF

Swiss-port # P51858 Human Hepatoma-derived growth factor

Gene Symbol HDGF
Gene Full Name hepatoma-derived growth factor
Background HDGF is a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. High levels of expression of this gene enhance the growth of many tumors. This gene was thought initially to be located on chromosome X; however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2016]
Function HDGF Isoform 1: Acts as a transcriptional repressor (PubMed:17974029). Has mitogenic activity for fibroblasts (PubMed:11751870, PubMed:26845719). Heparin-binding protein (PubMed:15491618).

Isoform 2: Does not have mitogenic activity for fibroblasts (PubMed:26845719). Does not bind heparin (PubMed:26845719).

Isoform 3: Has mitogenic activity for fibroblasts (PubMed:26845719). Heparin-binding protein (PubMed:26845719). [UniProt]
Cellular Localization Cytoplasm. Nucleus.
Highlight Related products:
HDGF antibodies; HDGF ELISA Kits; Anti-Rabbit IgG secondary antibodies;
Related news:
The most sensitive human HDGF ELISA kit
The role of HDGF in tumor angiogenesis
Calculated MW 27 kDa
PTM Sumoylated with SUMO1. Sumoylation prevents binding to chromatin.

Images (3) Click the Picture to Zoom In

  • ARG55689 anti-HDGF antibody ICC/IF image

    Immunofluorescence: SK-BR-3 cells stained with ARG55689 anti-HDGF antibody (green). DAPI (blue) for nuclear staining.

  • ARG55689 anti-HDGF antibody IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded Human hepatocarcinoma tissue stained with ARG55689 anti-HDGF antibody.

  • ARG55689 anti-HDGF antibody WB image

    Western blot: 35 µg of HeLa cell lysate stained with ARG55689 anti-HDGF antibody.