ARG46194
anti-HES5 antibody
anti-HES5 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes HES5 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | HES5 |
| Antigen Species | Human |
| Immunogen | A 19 amino acid synthetic peptide within the first 50 amino acids of human HES5. |
| Conjugation | Un-conjugated |
| Alternate Names | HES5; Transcription factor HES-5; bHLHb38; Class B basic helix-loop-helix protein 38; Hairy and enhancer of split 5 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 17 kDa |
Properties
| Purification | Affinity chromatography purified |
|---|---|
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | HES5 |
| Gene Full Name | hes family bHLH transcription factor 5 |
| Background | This gene encodes a member of a family of basic helix-loop-helix transcriptional repressors. The protein product of this gene, which is activated downstream of the Notch pathway, regulates cell differentiation in multiple tissues. Disruptions in the normal expression of this gene have been associated with developmental diseases and cancer. [provided by RefSeq, Dec 2008] |
| Function | Transcriptional repressor of genes that require a bHLH protein for their transcription. Plays an important role as neurogenesis negative regulator (By similarity). [UniProt] |
| Cellular Localization | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00380, ECO:0000255|PROSITE-ProRule:PRU00981} |
| Calculated MW | 18 kDa |
Images (2) Click the Picture to Zoom In
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ARG46194 anti-HES5 antibody IHC-P image
Immunohistochemistry: Human spleen stained with ARG46194 anti-HES5 antibody.
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ARG46194 anti-HES5 antibody WB image
Western blot: Raji stained with ARG46194 anti-HES5 antibody.
