anti-HLA B7 antibody [BB7.1] (PE)

anti-HLA B7 antibody [BB7.1] (PE) for Flow cytometry and Human,Primates

Immune System antibody


Product Description PE-conjugated Mouse Monoclonal antibody [BB7.1] recognizes HLA B7
Tested Reactivity Hu, NHuPrm
Tested Application FACS
Specificity The clone BB7.1 recognizes the HLA-B7 antigen. Although highly specific, it can cross-react with HLA-B42 antigen.
Host Mouse
Clonality Monoclonal
Clone BB7.1
Isotype IgG1
Target Name HLA B7
Immunogen Papain solubilised HLA-A2, B7
Conjugation PE
Alternate Names SPDA1; HLAB; AS; MHC class I antigen B*7; HLA class I histocompatibility antigen, B-7 alpha chain

Application Instructions

Application Suggestion
Tested Application Dilution
FACS10 µl / 10^6 cells
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Purification Note The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
Buffer PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA
Preservative 15 mM Sodium azide
Stabilizer 0.2% (w/v) high-grade protease free BSA
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 3106 Human HLA-B

Swiss-port # P01889 Human HLA class I histocompatibility antigen, B-7 alpha chain

Gene Symbol HLA-B
Gene Full Name major histocompatibility complex, class I, B
Background HLA-B7 allele of human HLA class I major histocompatibility (MHC) antigen indicates higher risk of breast cancer and cervical cancer. Expression of HLA-B7 together with HLA-B27 is associated with increased susceptibility to spondyloarthropaties. Flow cytometry detection of these two alleles is being used to screen for patients, who suffer from inflammatory disorders affecting the sacroiliac and intervertebral joints, such as ankylosing spondylosis (AS). The HLA-B7 antigen (11 alleles) is expressed in 22% of healthy Caucasian individuals.
Function Involved in the presentation of foreign antigens to the immune system. [UniProt]
Research Area Immune System antibody
Calculated MW 40 kDa
PTM Polyubiquitinated in a post ER compartment by interaction with human herpesvirus 8 MIR1 protein. This targets the protein for rapid degradation via the ubiquitin system (By similarity).

Clone References

Monoclonal antibodies for analysis of the HLA system.

Brodsky FM et al.
Immunol Rev.,  (1979)