ARG44675
anti-HPRT1 antibody
anti-HPRT1 antibody for Immunoprecipitation and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes HPRT1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IP |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Target Name | HPRT1 |
| Antigen Species | Human |
| Conjugation | Un-conjugated |
| Alternate Names | HPRT1; Hypoxanthine Phosphoribosyltransferase 1; HGPRT; HPRT; Hypoxanthine Guanine Phosphoribosyl Transferase; Hypoxanthine-Guanine Phosphoribosyltransferase; EC 2.4.2.8; HGPRTase; Hypoxanthine-Guanine Phosphoribosyltransferase 1; Testicular Tissue Protein Li 89; Lesch-Nyhan Syndrome |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P00492 Human Hypoxanthine-guanine phosphoribosyltransferase |
|---|---|
| Gene Symbol | HPRT1 |
| Gene Full Name | Hypoxanthine Phosphoribosyltransferase 1 |
| Background | The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout. |
| Function | Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway. |
| Cellular Localization | Cytoplasm |
| Calculated MW | 25 kDa |
Images (1) Click the Picture to Zoom In
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ARG44675 anti-HPRT1 antibody IP image
Immunoprecipitation: HEK293 lysate immunoprecipitated with 2.5 µg of ARG44675 anti-HPRT1 antibody.
