ARG11180
anti-Helicobacter pylori CagA antibody [5C6]
anti-Helicobacter pylori CagA antibody [5C6] for ELISA and Helicobacter pylori
Microbiology and Infectious Disease antibody
Overview
| Product Description | Mouse Monoclonal antibody [5C6] recognizes Helicobacter pylori CagA |
|---|---|
| Tested Reactivity | H. pylori |
| Tested Application | ELISA |
| Specificity | Cross-reaction with other proteins has not been identified. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 5C6 |
| Isotype | IgG1 Kappa |
| Target Name | Helicobacter pylori CagA |
| Immunogen | A highly immunogenic 32kD CagA fragment, recombinant |
| Conjugation | Un-conjugated |
| Alternate Names | cagA; cytotoxin associated gene A |
Application Instructions
| Application Note | ELISA: HRP conjugated anti-CagA clone 5C6 can detect recombinant CagA antigen in combination with anti-CagA clone 10E9 (ARG10169) coated ELISA plates. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
|---|
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein G |
| Buffer | 0.01M PBS (pH 7.0) |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | cagA |
|---|---|
| Gene Full Name | cytotoxin associated gene A |
| Background | Helicobacter pylori (H. pylori), a spiral rod shaped gram-negative bacterium, is frequently found in the stomach. In infected populations, 10-20% may develop gastritis and gastric ulcer and 1-2% may develop cancer. The genome of H. pylori isolates from carriers with symptoms contains a 40kb pathogenicity island encoding H. pylori cytotoxin, cytotoxin associated gene A protein (CagA) and other virulence associated factors. CagA is used as a biomarker for virulent H. pylori strains. |
| Highlight | Related products: Helicobacter pylori antibodies; Helicobacter pylori ELISA Kits; Helicobacter pylori Duos / Panels; Anti-Mouse IgG secondary antibodies; Related news: Tools for studying H. pylori diseases |
| Research Area | Microbiology and Infectious Disease antibody |
