ARG67334
anti-Histone H3 L-Lactyl (Lys18) antibody [7H06]
anti-Histone H3 L-Lactyl (Lys18) antibody [7H06] for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
Overview
| Product Description | Rabbit Monoclonal antibody [7H06] recognizes Histone H3 L-Lactyl (Lys18) |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | 7H06 |
| Isotype | IgG, Kappa |
| Target Name | Histone H3 |
| Conjugation | Un-conjugated |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 17 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A |
| Purification Note | PBS, 50% Glycerol, 0.05% Proclin 300, 0.05% BSA |
| Purity | 0.05% Proclin 300 |
| Buffer | 50% Glycerol and 0.05% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | H3F3A/H3F3B (Histone H3 family) |
|---|---|
| Gene Full Name | Histone H3.1/H3.2/H3.3 |
| Function | Core component of nucleosome; nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility. L-Lactylation is generally linked to gene activation. Tissue specificity: Blood, Epithelium, Kidney, Lung, Ovary, Spleen, Uterus. |
| Cellular Localization | Nucleus. Chromosome. |
| Calculated MW | 15 kDa |
| PTM | L-Lactylation at Lys18 (H3K18la); part of the broader histone code including methylation, phosphorylation, ubiquitination. |
