anti-IFIT2 antibody

anti-IFIT2 antibody for Western blot and Human

Immune System antibody; Signaling Transduction antibody


Product Description Rabbit Polyclonal antibody recognizes IFIT2
Tested Reactivity Hu
Tested Application WB
Host Rabbit
Clonality Polyclonal
Target Name IFIT2
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide corresponding to aa. 307-335 (Center) of Human IFIT2 (NP_001538.4).
Conjugation Un-conjugated
Alternate Names IFI-54K; IFIT-2; IFI-54; ISG54; ISG-54 K; cig42; Interferon-induced protein with tetratricopeptide repeats 2; Interferon-induced 54 kDa protein; P54; GARG-39; G10P2; IFI54; ISG-54K

Application Instructions

Application Suggestion
Tested Application Dilution
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control 293


Purification Protein A purified
Buffer PBS and 0.09% (W/V) Sodium azide
Preservative 0.09% (W/V) Sodium azide
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 3433 Human IFIT2

Swiss-port # P09913 Human Interferon-induced protein with tetratricopeptide repeats 2

Gene Symbol IFIT2
Gene Full Name interferon-induced protein with tetratricopeptide repeats 2
Function IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2'-O-methylation of the 5' cap. The ribose 2'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation (cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis. [UniProt]
Cellular Localization Cytoplasm. Endoplasmic reticulum
Research Area Immune System antibody; Signaling Transduction antibody
Calculated MW 55 kDa

Images (1) Click the Picture to Zoom In

  • ARG54736 anti-IFIT2 antibody WB image

    Western blot: 35 µg of 293 cell lysate stained with ARG54736 anti-IFIT2 antibody.