anti-IGF2BP3 antibody

anti-IGF2BP3 antibody for Western blot and Human

Cancer antibody; Gene Regulation antibody


Product Description Mouse Monoclonal antibody recognizes IGF2BP3
Tested Reactivity Hu
Tested Application WB
Host Mouse
Clonality Monoclonal
Isotype IgG1
Target Name IGF2BP3
Antigen Species Human
Immunogen Purified recombinant Human IGF2BP3 protein fragments expressed in E.coli.
Conjugation Un-conjugated
Alternate Names KOC; CT98; IMP3; KOC1; IMP-3; VICKZ3

Application Instructions

Application Suggestion
Tested Application Dilution
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Observed Size 70 kDa


Form Liquid
Purification Affinity purified
Buffer PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Concentration 0.6 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 10643 Human IGF2BP3

Swiss-port # O00425 Human Insulin-like growth factor 2 mRNA-binding protein 3

Gene Symbol IGF2BP3
Gene Full Name insulin like growth factor 2 mRNA binding protein 3
Background The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq, Jul 2008]
Function RNA-binding factor that may recruit target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 3'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to beta-actin/ACTB and MYC transcripts. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs.
Cellular Localization Nucleus. Cytoplasm. [UniProt]
Research Area Cancer antibody; Gene Regulation antibody
Calculated MW 64 kDa

Images (1) Click the Picture to Zoom In

  • ARG54133 anti-IGF2BP3 antibody WB image

    Western blot: Jurkat cell lysate stained with ARG54133 anti-IGF2BP3 antibody at 1:1000 dilution.