anti-IL16 antibody (Biotin)

anti-IL16 antibody (Biotin) for ELISA and Human


Product Description Biotin-conjugated Rabbit Polyclonal antibody recognizes IL16
Tested Reactivity Hu
Tested Application ELISA
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name IL16
Antigen Species Human
Immunogen E. coli derived recombinant Human IL16.
Conjugation Biotin
Alternate Names prIL-16; Lymphocyte chemoattractant factor; PRIL16; IL-16; NIL16; LCF; Pro-interleukin-16

Application Instructions

Application Suggestion
Tested Application Dilution
ELISADirect: 0.25 - 1.0 µg/ml
Sandwich: 0.25 - 1.0 µg/ml with ARG65994 as a capture antibody
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Purification Purified by affinity chromatography.
Buffer PBS (pH 7.2)
Concentration 1 mg/ml
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 3603 Human IL16

Swiss-port # Q14005 Human Pro-interleukin-16

Gene Symbol IL16
Gene Full Name interleukin 16
Background The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
Function Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.

Isoform 1 may act as a scaffolding protein that anchors ion channels in the membrane.

Isoform 3 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells. [UniProt]
Calculated MW 142 kDa
PTM Isoform 3 is synthesized as a chemo-attractant inactive precursor in hemopoietic tissues and is proteolytically cleaved by caspase-3 to yield IL-16.

Images (2) Click the Picture to Zoom In

  • ARG65995 anti-IL16 antibody (Biotin) standard curve image

    Direct ELISA: ARG65995 anti-IL16 antibody (Biotin) at 0.25 - 1.0 µg/ml results of a typical standard run with optical density reading at 405 - 650 nm.

  • ARG65995 anti-IL16 antibody (Biotin) standard curve image

    Sandwich ELISA: ARG65995 anti-IL16 antibody (Biotin) as a detection antibody at 0.25 - 1.0 µg/ml combined with ARG65994 anti-IL16 antibody as a capture antibody. Results of a typical standard run with optical density reading at 405 - 650 nm.